Lymphoma is a type of blood cancer. There are many different subtypes of the disease. Getting the right diagnosis is vital to getting the right treatment.

At Baptist Health Miami Cancer Institute, you’ll find acclaimed physicians who specialize in diagnosing and treating lymphoma. We use the latest diagnostic methods to precisely confirm the type and stage of your disease, so you receive the most effective treatment. Our techniques can identify even the rarest types of lymphoma.

Once we have a diagnosis, our team of cancer specialists from many areas of medicine works together to develop a treatment plan just for you. That plan includes the most up-to-date therapies and compassionate, whole-person care at every stage of your cancer journey.

What is lymphoma?

Lymphoma is a cancer that affects a type of white blood cells called lymphocytes. The disease typically occurs in your lymph nodes and other lymphatic tissue. Your lymphatic system is part of your immune system.

Lymphoma happens when the genetic information (DNA) that controls lymphocyte production no longer works correctly. This causes the body to produce dysfunctional lymphocytes that grow uncontrollably.

Types of Lymphoma

There are more than 70 different types of lymphoma. They’re organized into two groups:

  • Hodgkin lymphoma. This type of lymphoma mostly affects young adults, but it isn’t common. It involves large cancer cells called Hodgkin Reed-Sternberg cells. There are two main subtypes of Hodgkin’s disease: nodular lymphocyte-predominant Hodgkin lymphoma and classical Hodgkin lymphoma. Classical Hodgkin lymphoma is further broken down into four sub-subtypes:
    • Lymphocyte-depleted
    • Lymphocyte-rich
    • Mixed cellularity
    • Nodular sclerosis
  • Non-Hodgkin lymphoma. This type of lymphoma is more common and mostly affects older adults. It is organized into two groups: B-cell lymphomas and T-cell lymphomas. Types of non-Hodgkin lymphoma include:
    • Anaplastic large cell lymphoma
    • Angioimmunoblastic lymphoma
    • Burkitt’s lymphoma
    • Cutaneous T-cell lymphoma
    • Diffuse large B-cell lymphoma (DLBCL)
    • Follicular lymphoma
    • Mantle cell lymphoma
    • Marginal zone lymphoma
    • Peripheral T-cell lymphoma
    • Primary mediastinal B-cell lymphoma
    • Small lymphocytic lymphoma and chronic lymphocytic leukemia (SLL/CLL)

Lymphoma types also differ by their rate of development — some types progress slowly while others grow quickly.

Outlook for lymphoma patients

All types of lymphoma are serious. Generally, however, the outlook for people with Hodgkin lymphoma is better than that for those with non-Hodgkin lymphoma. If you’re diagnosed with Hodkin lymphoma, you’re about 90 percent as likely to be alive five years after your diagnosis compared to someone who doesn’t have the disease. Survival rates are even higher when your cancer is diagnosed in the earliest stages.

Those with non-Hodgkin lymphoma are about 74 percent as likely as those without the disease to be alive five years after diagnosis. However, there’s wide variation among those with different types and stages of the disease. With treatment, many people go into remission and live for years, showing no sign of lymphoma.

Risk Factors for Lymphoma

Physicians don’t yet know what causes lymphoma. One possible risk factor is having a weak immune system. Your immune system may weaken if you:

  • Are exposed to infections like HIV, Helicobacter pylori, hepatitis C or the human T-cell leukemia/lymphotropic virus
  • Have an autoimmune disease
  • Use immunosuppressants after an organ transplant

Preventing Lymphoma

There are no proven ways to prevent lymphoma. Maintaining a healthy lifestyle to protect your immune system and avoid infection could possibly lower your risk, but more research is needed.

Clinical Trials

Clinical Trials

Our cancer specialists at Baptist Health Miami Cancer Institute expertly combine the best of clinical research with the best of patient care to deliver your best outcomes.

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